What Is Small Intestine Fungal Overgrowth (SIFO)? SIFO stands for small intestine fungal overgrowth and, as the name suggests, is when there is an overgrowth of fungi, often candida albicans, in the small intestine. In the past, SIFO was only really diagnosed in HIV-positive patients, during steroid therapy and antibiotic therapy in cancer patients, and
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