Coffee Improves Human Health

Dementia And Stroke

Globally, over 50 million individuals had dementia in 2019. This number is anticipated to increase to 152 million by 2050. Given the limited therapeutic value of drugs currently used for treating dementia, identifying the preventable risk factors of dementia is of high priority.

Stroke, accounting for 10% of all deaths globally, is a leading cause of all disability-adjusted life years. Although the age-standardised incidence and mortality of stroke have decreased globally in the past 2 decades, the absolute numbers of stroke cases and deaths have increased. Stroke and dementia confer risks for each other and share some of the same, largely modifiable, risk and protective factors. A population-based longitudinal study found that stroke and dementia shared about 60% risk and protective factors.

Post-stroke dementia refers to any dementia occurring after stroke. Poststroke dementia poses a significant public health problem, with 30% of stroke survivors suffering from dementia

Coffee’s Health Properties

Coffee and tea contain caffeine and is a rich source of antioxidants and other bioactive compounds. They have been reported to play neuroprotective roles, such as anti-oxidative stress, anti-inflammation, inhibition of amyloid-beta aggregation (see in Alzheimer’s), and an anti-apoptotic effect.

Coffee Reduces Risk of Stroke And Dementia

• This study included 365,682 participants (50 to 74 years old) from the UK Biobank who reported their coffee and tea consumption.
• We found that coffee intake of 2 to 3 cups per day or tea intake of 3 to 5 cups per day or their combination intake of 4 to 6 cups per day were linked with the lowest hazard ratio (HR) of incident stroke and dementia.
• Drinking 2 to 3 cups of coffee with 2 to 3 cups of tea daily were associated with a 32% lower risk of stroke and a 28% lower risk of dementia.
• Intake of coffee alone or in combination with tea was associated with lower risk of poststroke dementia.